• Robert O. Stuart, William Wachsman, Charles C. Berry, Karen Arden, Steven Goodison, Igor Klacansky, Dan Masys, Michael McClelland, Jessica Wang-Rodriquez, Linda Wasserman, Yipeng Wang, Anne Sayers, Veta Kalcheva, David Tarin, and Dan Mercola.
    In silico dissection of cell-type associated patterns of gene expression in prostate cancer.
    Proc. Natl. Acad. Sci U.S.A. 2004; 101: 615-620.


  • Jun Hayakawa, Shalu Mittal, Yipeng Wang, Kemal Korkmaz, Mashide Ohmichi, Eileen Adamson, Michael McClelland, Dan Mercola.
    Identification of Promoters Boundby c-Jun/ATF2 during Rapid Large-Scale Gene Activation following Genotoxic Stress
    Molecular Cell 2004;16:521-535.


  • Koziol JA, Feng AC, Jia Z, Wang Y, McClelland M, Mercola D.
    The Wisdom of the Commons: Ensemble Tree Classifiers for Prostate Cancer Prognosis.
    Bioinformatics. 2008; 25: 54-60.


  • Yu J, Zhang SS, Saito K, Williams S, Arimura Y, Ma Y, Ke Y, Baron V, Mercola, D, Feng GS, Adamson E, Mustelin T.
    PTEN regulation by Akt-EGR1-ARF-PTEN axis.
    EMBO J. 2009; 28(1): 21-33.


  • Simoneau AR, Liao WX, Yi G, Hope CJ, Xie J, Holcombe RF, Jurnak FA, Mercola D, Hoang, BH,  Zi X, Li S, Liu F, Tang Y.
    WIF1, a Wnt pathway inhibitor, regulates SKP2 and c-myc expression leading to G1 arrest and growth inhibition of human invasive urinary bladder cancer cells.
    Mol Cancer Ther  2009; 8: 458-68.



  • Major JM, Klonoff-Cohen HS, Pierce JP, Slymen DJ, Saltzstein SL, Macera, C., Mercola, Dan, Kattan, M.W.
    Prostate Cancer Postoperative Nomogram Scores and Obesity.
    PLoS ONE. 2011; 6(2): e17382.


  • Yipeng Wang, Xiao-Qin Xia, Zhenyu Jia, Anne Sawyers, Huazhen Yao, Jessica Wang-Rodriquez, Michael, McClelland, Dan Mercola.
    In silico estimates of tissue components in surgical samples based on expression profiling data.
    Cancer Research. 2010; 70(16): 6448-6455.


  • Zhenyu Jia, Yipeng Wang, Anne Sawyers, Huazhen Yao, Farahnaz Rahmatpanah, Xiao-Qin Xia, Qiang Xu, Rebecca Pio, Tolga Turan, James A. Koziol, Stephen Goodison, Philip Carpenter, Jessica Wang-Rodriquez, Anne Simoneau, Frank Meyskens, Manuel Sutton, Waldemar Lernhardt, Thomas Beach, Michael McClelland and Dan Mercola.
    Diagnosis of Prostate Cancer Using Differentially Expressed Genes in Stroma.
    Cancer Research, 2011; 71(7): 2476-2487



  • Zhenyu Jia, Yipeng Wang, Yuanjie Hu, Christine McLaren, Yingyan Yu, Kai Ye, Xiao-Qin Xia, James, A. Koziol, Waldemar Lernhardt, Michael McClelland, Dan Mercola.
    A Sample Selection Strategy to Boost the Statistical Power of Signature Detection in Cancer Expression Profile Studies
    Anti-Cancer AGENTS IN Medicinal Chemistry 2013; 12: 203-211.


  • Zhenyu Jia, Farahnaz Rahmatpanah, Xin Chen, Waldemar Lernhardt, Yipeng Wang, Xiao-Qin Xia, Anne Sawyers, Michael McClelland, and Dan Mercola.
    Expression changes in the stroma of prostate cancer predict subsequent relapse.
    PLoS ONE 2012; 7(8): e41371.


  • Xin Chen, Shizhong Xu, Farah Rahmatpanah, Michael McClelland, Zhenyu Jia, and Dan Mercola.
    An accurate prostate cancer prognosticator using a seven-gene signature plus Gleason score derived by taking cell type-heterogeneity into account.
    PloS ONE, 2012; 7(9): e45178.


  • Khan S, Jutzy JM, Valenzuela MM, Turay D, Aspe JR, Ashok A, Mirshahidi S, Mercola D, Lilly MB, Wall NR.
    Plasma-derived exosomal survivin, a plausible biomarker for early detection of prostate cancer.
    PLoS ONE. 2012;7(10):e46737.



  • Rebecca Pio, Zhenyu Jia, Veronioque T. Baron and Dan Mercola.
    Early Growth Response Gene 3 (Egr3) is highly over-expressed in non-relapsing prostate cancer but not in relapsing prostate cancer.
    PloS ONE, 2013; 8 (1):. e54093.


  • Xiao-Qin Xia,Zhenyu Jia, Steffen Porwollik, Fred Long, Claudia Hoemme,Kai Ye, Carsten Müller-Tidow, Michael McClelland,and Yipeng Wang.
    Evaluating Oligonucleotide Properties for DNA Microarray Probe Design
    Nucleic Acids Res (2010) 38 (Vol 11): e121   



  • Matthew A. Kinseth, Zhenyu Jia, Farahnaz Rahmatpanah, Anne Sawyers, Manuel Sutton, Jessica Wang-Rodriguez, Kathleen L. McGuire and Dan Mercola.
    Altered Gene Expression by Prostate Tumor and Stroma in African American and Cell-type Matched Caucasians Reveal that Stroma is the Site of Aggressive Changes.
    Int. J. Cancer,  Online June 10, 2013,


  • Xuejiao Tian, Saiyang Zhang, Hong-Min Liu, Yan-Bing Zhang, Christopher A Blair,  Dan Mercola, Paolo Sassone-Corsi and Xiaolin Zi1.
    Histone Lysine-Specific Methyltransferases and Demethylases in Carcinogenesis.
    Current Cancer Drug Targets, 2013;13: 558-579.


  • Chung Lee;  Qiang Zhang, James Kozlowski, Charles Brendler, Marcelo B. Soares, Atrya Dash, Michael McClelland, and Dan Mercola,
    Natural products and transforming growth factor-beta (TGF-β) signaling in cancer development and progression.
    In:  Current Cancer Drug Targets; Bentham Science Publishers. 2013  (in press).


Other Relevant Publications

  • Andriole, G.L., et al., Is there a better way to biopsy the prostate? Prospects for a novel transrectal systematic biopsy approach.
    Urology, 2007. 70(6 Suppl): p. 22-6.
  • Ayala, G., et al., Reactive stroma as a predictor of biochemical-free recurrence in prostate   cancer.
    Clin Cancer Res, 2003. 9(13): p. 4792-801.
  • Cunha, G.R., et al., Role of the stromal microenvironment in carcinogenesis of the prostate.Int J Cancer, 2003. 107(1): p. 1-10.
  • Condon, M.S., The role of the stromal microenvironment in prostate cancer.
    Semin Cancer Biol, 2005. 15(2): p. 132-7.